Ab00208-2.3 Anti-CD5 [YTS 121.5.2]

Description: Recombinant monoclonal antibody to CD5. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YTS 121.5.2. This antibody was created using our proprietary Fc Silent™ engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors.

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Species and Isotype: Mouse IgG2a, Fc Silent™, kappa
Clone Number: YTS 121.5.2
UniProt Accession Number of Target Protein: P13379
Alternative Name(s) of Target: lyt-1; T-cell surface glycoprotein CD5; Lymphocyte antigen 1; Ly-1; Lyt-1
Published Application(s): FC; IHC
Published Species Reactivity: Mouse
Immunogen: CBA mouse thymocytes.
Specificity: Recognises murine CD5 (Lyt-1) a cell surface glycoprotein expressed by 95% of T-lymphocytes and 72% of peripheral blood lymphocytes.
Antibody First Published in:
Cobbold SP, Jayasuriya A, Nash A, Prospero TD, Waldmann H. Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature. 1984 Dec 6-12;312(5994):548-51. PMID:6150440

Product Form

Purification: Protein A affinity purified

Supplied in: Vivopure 100 mg: PBS only, with >98% antibody purity and <1 EU/mg guaranteed. Vivopure 10 mg: PBS only, with >98% antibody purity and <1 EU/mg guaranteed. Vivopure 25 mg: PBS only, with >98% antibody purity and <1 EU/mg guaranteed. Standard size: PBS with 0.02% Proclin 300.

Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.

Product Code: Ab00208-2.3