Ab00369-1.1 Anti-Histone H2B [LG11-2]
Description: Recombinant monoclonal antibody to Histone H2B. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma LG11-2.
Clone Number: LG11-2
UniProt Accession Number of Target Protein: Q96A08
Alternative Name(s) of Target: H2B
Published Application(s): ELISA
Published Species Reactivity: Human; mouse
Immunogen: Residues 1-25 of human H2B.
Specificity: The antiody binds specifically to the N-terminus of H2B, residues 6-18.
Application Notes: The antibody binds to the N-terminus of histone H2B, which is one of the 5 core histone proteins involved in the formation of chromatin.
Antibody First Published in:
Monestier et al. 2001 Molecular and structural properties of three autimmune IgG monoclonal antibodies to histone H2B. Journal of Biological Chemistry 2000; 275(18)13558-13563 PMID:10788471 Note on publication: Describes the generation of three anti H2B monoclonal antibodies from lupus-prone mice.
Supplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
This reformatted mouse antibody was made using the variable domain sequences of the original mouse IgG2a format for improved compatibility with existing reagents, assays and techniques.
Species and Isotype: Mouse IgG1, kappaClone Number: LG11-2
UniProt Accession Number of Target Protein: Q96A08
Alternative Name(s) of Target: H2B
Published Application(s): ELISA
Published Species Reactivity: Human; mouse
Immunogen: Residues 1-25 of human H2B.
Specificity: The antiody binds specifically to the N-terminus of H2B, residues 6-18.
Application Notes: The antibody binds to the N-terminus of histone H2B, which is one of the 5 core histone proteins involved in the formation of chromatin.
Antibody First Published in:
Monestier et al. 2001 Molecular and structural properties of three autimmune IgG monoclonal antibodies to histone H2B. Journal of Biological Chemistry 2000; 275(18)13558-13563 PMID:10788471 Note on publication: Describes the generation of three anti H2B monoclonal antibodies from lupus-prone mice.
Product Form
Purification: Protein A affinity purifiedSupplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
Important note – This product is for research use only. It is not intended for use in therapeutic or diagnostic
procedures for humans or animals.
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