Description: Recombinant monoclonal antibody to Histone H2B. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma LG11-2.
Species and Isotype: Mouse IgG1, kappa
Clone Number: LG11-2
UniProt Accession Number of Target Protein: Q96A08
Alternative Name(s) of Target: H2B
Published Application(s): ELISA
Published Species Reactivity: Human; mouse
Immunogen: Residues 1-25 of human H2B.
Specificity: The antiody binds specifically to the N-terminus of H2B, residues 6-18.
Application Notes: The antibody binds to the N-terminus of histone H2B, which is one of the 5 core histone proteins involved in the formation of chromatin.
Antibody First Published in:
Monestier et al. 2001 Molecular and structural properties of three autimmune IgG monoclonal antibodies to histone H2B. Journal of Biological Chemistry 2000; 275(18)13558-13563 PMID:10788471 Note on publication: Describes the generation of three anti H2B monoclonal antibodies from lupus-prone mice.

Product Form

Purification: Protein A affinity purified
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.