Ab00532-1.1 Anti-alpha-gal epitope [m86]
Description: Recombinant monoclonal antibody to alpha-gal epitope. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma m86.
Clone Number: m86
UniProt Accession Number of Target Protein:
Alternative Name(s) of Target: Gal-alpha-1 – 3Gal-beta-1 – 4GlcNAc-R
Published Application(s): FC; ELISA
Published Species Reactivity: Species independent
Immunogen: Rabbit red cells injected into alpha 1,3 galactosyltransferase knock-out mice.
Specificity: This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids.
Application Notes: This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from non-primate animals.
Antibody First Published in:
Chen, Radic and Galili Genes coding evolutionary novel anti-carbohydrate antibodies: studies on anti-Gal production in alpha 1,3 galactosyltransferase knock out mice. Mol Immunol. 2000 Jun;37(8):455-66. PMID:11090880 Note on publication: Describes the generation and characterization of anti-gal epitope antibodies raised in alpha 1,3 galactosyltransferase knock-out mice.
Concentration: See vial label.
This reformatted murine antibody was made using the variable domain sequences of the original mouse IgM format, for improved compatibility with existing reagents, assays and techniques.
Species and Isotype: Mouse IgG1, kappaClone Number: m86
UniProt Accession Number of Target Protein:
Alternative Name(s) of Target: Gal-alpha-1 – 3Gal-beta-1 – 4GlcNAc-R
Published Application(s): FC; ELISA
Published Species Reactivity: Species independent
Immunogen: Rabbit red cells injected into alpha 1,3 galactosyltransferase knock-out mice.
Specificity: This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids.
Application Notes: This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from non-primate animals.
Antibody First Published in:
Chen, Radic and Galili Genes coding evolutionary novel anti-carbohydrate antibodies: studies on anti-Gal production in alpha 1,3 galactosyltransferase knock out mice. Mol Immunol. 2000 Jun;37(8):455-66. PMID:11090880 Note on publication: Describes the generation and characterization of anti-gal epitope antibodies raised in alpha 1,3 galactosyltransferase knock-out mice.
Product Form
Purification: Protein A affinity purified Supplied in: Bulk size: PBS only. Standard size: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°CConcentration: See vial label.
Important note – This product is for research use only. It is not intended for use in therapeutic or diagnostic
procedures for humans or animals.
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