Description: Recombinant monoclonal antibody to alpha-gal epitope. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma m86.
Species and Isotype: Mouse IgG1, kappa
Clone Number: m86
UniProt Accession Number of Target Protein:
Alternative Name(s) of Target: Gal-alpha-1 – 3Gal-beta-1 – 4GlcNAc-R
Published Application(s): FC; ELISA
Published Species Reactivity: Species independent
Immunogen: Rabbit red cells injected into alpha 1,3 galactosyltransferase knock-out mice.
Specificity: This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids.
Application Notes: This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from non-primate animals.
Antibody First Published in:
Chen, Radic and Galili Genes coding evolutionary novel anti-carbohydrate antibodies: studies on anti-Gal production in alpha 1,3 galactosyltransferase knock out mice. Mol Immunol. 2000 Jun;37(8):455-66. PMID:11090880 Note on publication: Describes the generation and characterization of anti-gal epitope antibodies raised in alpha 1,3 galactosyltransferase knock-out mice.

Product Form

Purification: Protein A affinity purified
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.