Ab00545-8.1 Anti-CD11C [OX-42]
Description: Recombinant monoclonal antibody to CD11C. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma OX-42.
Clone Number: OX-42
UniProt Accession Number of Target Protein:
Published Application(s): FC; IHC; IP
Published Species Reactivity: Rat
Immunogen: Resident peritoneal cells from F1 hybrids between PVG-RT1c and PVG-RTu and between PVG-RT1c and DA-RT1a rats.
Specificity:
Application Notes: This antibody recognises rat CD11c, the receptor for iC3 strongly expressed on macrophages. Binding of this antibody does not interfere with phagocytosis.
Antibody First Published in:
Robinson, White, Mason Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. 1986 Immunology 57:239 PMID:3512425 Note on publication: Describes the generation and characterisation of this antibody.
Supplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Species and Isotype: Rat IgG2b, kappaClone Number: OX-42
UniProt Accession Number of Target Protein:
Published Application(s): FC; IHC; IP
Published Species Reactivity: Rat
Immunogen: Resident peritoneal cells from F1 hybrids between PVG-RT1c and PVG-RTu and between PVG-RT1c and DA-RT1a rats.
Specificity:
Application Notes: This antibody recognises rat CD11c, the receptor for iC3 strongly expressed on macrophages. Binding of this antibody does not interfere with phagocytosis.
Antibody First Published in:
Robinson, White, Mason Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. 1986 Immunology 57:239 PMID:3512425 Note on publication: Describes the generation and characterisation of this antibody.
Product Form
Purification: Protein A affinity purifiedSupplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
Important note – This product is for research use only. It is not intended for use in therapeutic or diagnostic
procedures for humans or animals.
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