Description: Recombinant monoclonal antibody to CD11C. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma OX-42.
Species and Isotype: Rat IgG2b, kappa
Clone Number: OX-42
UniProt Accession Number of Target Protein:
Published Application(s): FC; IHC; IP
Published Species Reactivity: Rat
Immunogen: Resident peritoneal cells from F1 hybrids between PVG-RT1c and PVG-RTu and between PVG-RT1c and DA-RT1a rats.
Specificity:
Application Notes: This antibody recognises rat CD11c, the receptor for iC3 strongly expressed on macrophages. Binding of this antibody does not interfere with phagocytosis.
Antibody First Published in:
Robinson, White, Mason Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. 1986 Immunology 57:239 PMID:3512425 Note on publication: Describes the generation and characterisation of this antibody.

Product Form

Purification: Protein A affinity purified
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.