Description: Recombinant monoclonal antibody to alpha-4 integrin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 21.6.
Species and Isotype: Rabbit IgG, kappa
Clone Number: 21.6
UniProt Accession Number of Target Protein: P13612
Alternative Name(s) of Target: CD49D; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha
Published Application(s): ELISA; Block
Published Species Reactivity: Human
Immunogen: Alpha-4 integrin.
Specificity: This antibody binds to human alpha-4-integrin
Application Notes: This antibody binds to human alpha-4-integrin and can inhibit the binding of lymphocytes to endothelial cells, suppressing inflammation.
Methods of inhibiting alpha-4-dependent interactions with VCAM-1 with anti-VLA-4 antibodies Patent US8246958 Note on publication: Describes the use of this murine antibody and humanized counterpart, their affinities and biological function.

Product Form

Purification: Protein A affinity purified
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.