Description: Recombinant monoclonal antibody to Bet v 1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the B-cell line BAB2.
Species and Isotype: Rabbit IgG, kappa
Clone Number: BAB2
UniProt Accession Number of Target Protein: P15494
Alternative Name(s) of Target: Major Allergen from Birch Pollen; BETVIA
Published Application(s): ELISA; activate; WB
Published Species Reactivity: Birch (Betula pendula)
Immunogen: Bet v 1, a major allergen of the European white birch.
Specificity: This antibody binds to Bet v 1. It recognises amino acids 1-74 of recombinant Bet v 1 by Western Blot, whilst showing no binding to AA 75-160.
Application Notes: This antibody binds to Bet v 1 and appears to enhance binding of IgE as well as Bet v 1-induced immediate-type skin reactions and thus represent 'enhancing antibodies'.
Antibody First Published in:
Eibensteiner et al. Expression of a human IgG4 antibody, BAB2, with specificity for the major Birch pollen allergen, Bet v 1 in Escherichia coli: recombinant BAB2 Fabs enhance the allergic reaction. Int Arch Allergy Immunol. 1999 Feb-Apr;118(2-4):190-2. PMID:10224374 Note on publication: Describes the generation and characterization of this antibody.

Product Form

Purification: Protein A affinity purified
Supplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.