Anti-CD40 [G28.5] Standard size

Description: Recombinant monoclonal antibody to CD40. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma G28.5.
Isotype and Format: Human IgM, kappa
Clone Number: G28.5
Published Application(s): FC; IP; IHC; activate
Published Species Reactivity: Human
Immunogen: Human erythrocyte-rosette-negative tonsillar lymphocytes.
Specificity: 48 kD Type I glycoprotein, a member of the TNFR superfamily primarily expressed on normal or malignant B cells or B cell lines, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells.
Application Notes: This antibody detects CD40 by immunostaining. The original mouse IgG1 format was shown to stimular B-cells (Bishop 2012 and references therein).
Antibody First Published in:
Clark EA, Ledbetter JA. Proc Natl Acad Sci U S A. 1986 Jun;83(12):4494-8. PMID:3487090 Note on publication: Describes the making of the antibody, shows it recognised a 50-kDa polypeptide expressed on all B cells using immunoprecipitation and flow cytometry.

Product Form

This is a Standard size product. Purified antibody.
Purification: Affinity Purified using a recombinant lectin column
Supplied in: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Concentration: See vial label