Anti-CD18 [YTS 213.1] Standard size

Description: Recombinant monoclonal antibody to CD18. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YTS 213.1. This antibody was created using our proprietary Fc Silent™ engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors.
Isotype and Format: Rat IgG2a, Fc Silent™, kappa
Clone Number: YTS 213.1
Published Application(s): FC; IHC-Fr; IP; IF
Published Species Reactivity: Mouse
Immunogen: Mouse spleen cells.
Specificity: Recognises CD18 beta subunit of LFA-1 family.
Application Notes: This antibody recognizes murine CD18, which together with CD11b forms the complement receptor 3, also called the Macrophage 1 antigen MAC1. This antibody may be used in flow cytometry, IHC , IF and IP. The original rat IgG2a format was not known to block function.
Antibody First Published in:
McDole et al. Am J Pathol. 2010 Oct;177(4):1823-33. PMID:20813972 Note on publication: Describes the use of this antibody in IHC and IF.

Product Form

This is a Standard size product. Purified antibody.
Purification: Protein A affinity purified
Supplied in: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00203-7.4

Rat IgG2a

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Standard size 200 µg
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