Anti-CD5 [YTS 121.5.2]

Description:

Recombinant monoclonal antibody to CD5. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YTS 121.5.2.

Clone Name:

YTS 121.5.2

Published Application(s):

FC, IHC

Published Species Reactivity:

Mouse

Products based on this clone:

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Ab00208-2.0 Anti-CD5 [YTS 121.5.2]
Mouse
Mouse IgG2a
Purified, Vivopure
In Stock

Ab00208-2.3 Anti-CD5 [YTS 121.5.2]
Mouse
Mouse IgG2a
Fc Silent™
Purified, Vivopure
In Stock

Ab00208-8.1 Anti-CD5 [YTS 121.5.2]
Mouse
Rat IgG2b
Purified, Vivopure
In Stock

Ab00208-8.4 Anti-CD5 [YTS 121.5.2]
Mouse
Rat IgG2b
Fc Silent™
Purified, Vivopure
In Stock

Ab00208-23.0 Anti-CD5 [YTS 121.5.2]
Mouse
Rabbit IgG
Purified
In Stock

UniProt Accession Number of Target Protein: P13379

Alternative Name(s) of Target: Lyt-1; T-cell surface glycoprotein CD5; Lymphocyte antigen 1; Ly-1; Lyt-1; YTS121; YTS-121
Immunogen: CBA mouse thymocytes.

Specificity: Recognises murine CD5 (Lyt-1) a cell surface glycoprotein expressed by 95% of T-lymphocytes and 72% of peripheral blood lymphocytes.

Antibody first published in: Cobbold SP, Jayasuriya A, Nash A, Prospero TD, Waldmann H. Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature. 1984 Dec 6-12;312(5994):548-51. PMID:6150440

Flow-cytometry on mouse lymphocytes using Ab00208. Click on image for more details.

Flow-cytometry using anti-CD5 antibody YTS 121.5.2 (Ab00208) Mouse lymphocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of YTS 121.5.2 (Ab00208-23.0, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.

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