Anti-CD37 [WR17]

Description:

Recombinant monoclonal antibody to CD37. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma WR17.

Clone Name:

WR17

Published Application(s):

FC, IF, IHC

Published Species Reactivity:

Human

Products based on this clone:

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Ab00237-2.0 Anti-CD37 [WR17]
Human
Mouse IgG2a
Purified
In Stock

Ab00237-23.0 Anti-CD37 [WR17]
Human
Rabbit IgG
Purified
In Stock

UniProt Accession Number of Target Protein: P11049

Alternative Name(s) of Target: GP52-40; TSPAN26
Immunogen: Chronic lymphocytic leukaemia cells.

Specificity: Recognises human CD37.

Application Notes: This antibody binds CD37, staining, amongst others, B-cells and B-cell tumours.

Antibody first published in: Moore et al. Use of the monoclonal antibody WR17, identifying the CD37 gp40-45 Kd antigen complex, in the diagnosis of B-lymphoid malignancy J Pathol. 1987 May;152(1):13-21 PMID:3305845
Note on publication: Describes the characterization of this antibody.

IF staining of Daudi cells using Ab00237-23.0. Click on image for more details.

Immunofluorescence staining of fixed Daudi cells with anti-CD37 antibody WR17 (Ab00237) Immunofluorescence analysis of paraformaldehyde fixed Daudi cells on Shi-fix™ coverslips, permeabilized with 0.15% Triton and stained with the chimeric rabbit IgG version of WR17 (Ab00237-23.0) at 10 µg/ml for 1h followed by Alexa Fluor® 488 secondary antibody (1 µg/ml), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom Ab00237-23.0, DAPI, merged channels and an isotype control. The isotype control was stained with an anti-Fluorescein antibody (Ab102-23.0) followed by Alexa Fluor® 488 secondary antibody.

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