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- Ab00250-10.0 Anti-Influenza A HA [FLD21]
- H5N1 Influenza A Virus
- Human IgG1
- Purified
- In Stock
- Ab00250-23.0 Anti-Influenza A HA [FLD21]
- H5N1 Influenza A Virus
- Rabbit IgG
- Purified
- In Stock
Recombinant monoclonal antibody to Influenza A HA. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone FLD21.
Alternative Name(s) of Target: hemagglutinin; haemagglutinin
Immunogen: Made by immortalizing IgG-expressing B cells from patients who had recovered from infections with HPAI H5N1 Viruses.
Specificity: This clone can neutralize the hemagglutinin (HA) of a H5N1 strain of influenza A Virus.
Antibody first published in: Simmons et al. Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med. 2007 May;4(5):e178. PMID:17535101
ELISA using FLD21 (Ab00250) and Influenza A HA [A/Hong Kong/483/97 (H5N1)]. Binding curves of the human IgG chimeric version of the Anti-Influenza A HA antibody FLD21 (Ab00250-10.0; blue line) and isotype control (Ab00102-10.0, anti-fluorescein; yellow line) to an ELISA plate coated with Influenza A HA [A/Hong Kong/483/97 (H5N1)] at a concentration of 2.5 ug/ml. A 3-fold serial dilution from 3000 to 0.0169 ng/ml was performed using Ab00250 antibody. For signal detection, a 1:4000 dilution of a HRP-conjugated anti-human IgG antibody was used.