Anti-SARS-CoV S glycoprotein [S231]

Description:

Recombinant monoclonal antibody to SARS-CoV S glycoprotein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone S231.

Made with Antibody Sequences licensed from Humabs Biomed SA.

Clone Name:

S231

Published Application(s):

NTRL, ELISA

Published Species Reactivity:

SARS Coronavirus

Products based on this clone:

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Ab00265-10.0 Anti-SARS-CoV S glycoprotein [S231]
SARS Coronavirus
Human IgG1
Purified
In Stock

Ab00265-23.0 Anti-SARS-CoV S glycoprotein [S231]
SARS Coronavirus
Rabbit IgG
Purified
In Stock

Alternative Name(s) of Target: Severe Acute Respiratory Syndrome Coronavirus GP
Immunogen: Made by immortalizing IgG-expressing B cells from recovered SARS patients.

Specificity: SARS-CoV-neutralizing hmAbs, binds to SARS-CoV S glycoprotein, inhibiting the binding of the glycoprotein to human ACE2.

Antibody first published in: Rockx B, Corti D, Donaldson E, Sheahan T, Stadler K, Lanzavecchia A, Baric R. Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic Severe Acute Respiratory Syndrome CoronaVirus challenge. J Virol. 2008 Apr;82(7):3220-35. doi: 10.1128/JVI.02377-07. Epub 2008 Jan 16. PMID:18199635

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