United Kingdom (UK)
Recombinant monoclonal antibody to Syntaxin-1A. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma SP6.
Alternative Name(s) of Target: STX
Immunogen: Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates.
Specificity: This antibody binds to native and denatured syntaxin-1A. It is reported that this antibody specifically binds between amino acids 4-190.
Antibody first published in:
Wakabayashi et al. Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease. Brain Res. 1994 Dec 19;667(1):24-32 PMID:7895080
Note on publication:
Describes the use of this antibody in IHC on human brain affected by various pathologies (Alzheimer's Disease, Lewy body variant of Alzheimer's Disease and Lewy body disease).
Immunohistochemical staining of rabbit kidney using anti-syntaxin antibody Ab00297-1.1 Formalin fixed rabbit kidney slices were were stained with Ab00297-1.1 at 3 µg/ml.
Immunohistochemical staining of rat colon using anti-syntaxin antibody Ab00297-1.1 Formalin fixed rat colon slices were were stained with Ab00297-1.1 at 3 µg/ml.
Western Blot using anti-syntaxin antibody Ab00297-1.1 Rat kidney lysate was resolved on a 12% SDS PAGE gel and blots probed with Ab00297-1.1 at 3 µg/ml before being detected by a secondary antibody.