- {{heading}}
- Ab00298-1.1 Anti-SNAP-25 [SP12]
- Cat, Cow, Guinea Pig, Hamster, Pig, Rat, Human, Mouse
- Mouse IgG1
- Purified
- In Stock
- Ab00298-23.0 Anti-SNAP-25 [SP12]
- Cat, Cow, Guinea Pig, Hamster, Pig, Rat, Human, Mouse
- Rabbit IgG
- Purified
- In Stock
Recombinant monoclonal antibody to SNAP-25. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma SP12.
Alternative Name(s) of Target: Synaptosomal nerve-associated protein 25; CMS18; RIC-4; RIC4; SEC9; SNAP; SNAP-25; bA416N4.2; dJ1068F16.2; SUP; synaptosome associated protein 25kDal synaptosome associated protein 25
Specificity: This antibody binds to native and denatured SNAP-25.
Antibody first published in:
Wakabayashi et al. Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease. Brain Res. 1994 Dec 19;667(1):24-32 PMID:7895080
Note on publication:
Describes the use of this antibody in IHC on human brain affected by various pathologies (Alzheimer's Disease, Lewy body variant of Alzheimer's Disease and Lewy body disease).
Immunohistochemical staining of rabbit brain using anti-SNAP25 antibody Ab00298-1.1 Formalin fixed rabbit brain slices were were stained with a Ab00298-1.1 at 3 µg/ml.
Western Blot using anti-SNAP25 antibody Ab00298-1.1 Mouse brain (lane 1), mouse rectum (lane 2), mouse pancreas (lane 3), human lung cancer (lane 4), human breast cancer (lane 5) and Hela cell(lane 6) samples were resolved on a 12% SDS PAGE gel and blots probed with Ab00298-1.1 at 2 µg/ml before being detected by a secondary antibody. Bands correspondig to the expected 23 kDa SNAP25 protein were detected in mouse brain (along with likely oligomers) as well as in mouse rectum (faint). In this experiment no SNAP25 was dected in the other samples.