Anti-C3a-receptor [3G7] Bulk size

Description: Recombinant monoclonal antibody to C3a-receptor. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the scFv 3G7. This antibody was created using our proprietary Fc Silent™ engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors.
Isotype and Format: Human IgG1, Fc Silent™, kappa
Clone Number: 3G7
Published Application(s): ELISA; FC
Published Species Reactivity: Human
Immunogen: The 2e loop of the C3a receptor.
Specificity: Binds specifically to the 2e loop of the human C3a receptor, residues 185-193.
Application Notes: This scFv antibody binds to the 2e loop of the human C3a receptor, a G protein-coupled receptor stimulating chemotaxis, superoxide anion generation and granule enzyme release.
Antibody First Published in:
Hawlisch et al. 2001 Analytica Biochemistry 2001; 293(1):142-145 PMID:11373092 Note on publication: Describes the selection of scFv fragments with specificity for the C3a receptor from phage-display libraries.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00358-10.3-BT

Human IgG1

In stock
Standard size 200 µg
Custom conjugation:
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