Anti-Taq-Polymerase [TP7]

Description:

Recombinant monoclonal antibody to Taq-Polymerase. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma TP7.

Clone Name:

TP7

Published Application(s):

ELISA

Published Species Reactivity:

T. aquaticus

Products based on this clone:

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Ab00413-23.0 Anti-Taq-Polymerase [TP7]
T. aquaticus
Rabbit IgG
Purified
In Stock

Ab00413-1.1 Anti-Taq-Polymerase [TP7]
T. aquaticus
Mouse IgG1
Purified
In Stock

UniProt Accession Number of Target Protein: P19821

Alternative Name(s) of Target: Taq DNA Pol; Thermostable DNA-Polymerase I
Immunogen: Taq-Polymerase.

Specificity: This antibody binds to Taq-Polymerase with a Kd of 1 nM.

Application Notes: This antibody binds to Taq-polymerase, a thermostable DNA polymerase from a therophilic bacterium frequently used in PCR as its optimum temperature is about 75-80°C and is still active at temperatures up to 92.5°C. The antibody competes with DNA for Taq-binding.

Antibody first published in: Murali et al. Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. Protein Engineering 1998; 11(2):79-86 PMID:9605541
Note on publication: Describes the crystallisation of Taq-Polymerase with TP7 to identify the mechanism of inhibition and surface contacts.

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