Anti-Fatty acid-binding protein 4 (secreted) [Fab CA33] Standard size

Description: Recombinant monoclonal antibody to Fatty acid-binding protein 4 (secreted). Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the B-cell clone Fab CA33. This antibody is in our proprietary AbFab2™ recombinant F(ab2) format - based on Human IgG1 sequence with a short dimerization domain to improve stability and a his tag.
Isotype and Format: Human F(ab)2, AbFab2™ His-Tagged, kappa
Clone Number: Fab CA33
Published Application(s): Blocking; crystallography
Published Species Reactivity: Human
Immunogen: This antibody was generated by immunizising New Zealand White rabbits with a mixture containing recombinant human and mouse aP2 ( CAG33184.1 and CAJ18597.1, respectively).
Specificity: This antibod binds to both human and murine Fatty acid-binding protein.
Application Notes: The antibody binds to human Fatty-acid binding protein 4, which transports lipids and retinoic acids to their receptors. Administratio of CA33 t lowered fasting blood glucose, improved systemic glucose metabolism, increased systemic insulin sensitivity, and reduced fat mass and liver steatosis in obese mouse models.
Antibody First Published in:
Burak et al. Science Translational Medicine 2015; 7:319ra205 PMID:26702093 Note on publication: Describes the generation and characterisation of this antibody.

Product Form

This is a Standard size product. Purified antibody.
Purification: Purified by Immobilized Metal Affinity Chromatography
Supplied in: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00428-10.7

Human F(ab)2

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Standard size 100 µg
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