Anti-Cardiac Troponin I [scFv 180] Standard size

Description: Recombinant monoclonal antibody to Cardiac Troponin I. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the scFv scFv 180.
Isotype and Format: Mouse IgG1, lambda
Clone Number: scFv 180
Published Application(s): WB; SPR
Published Species Reactivity: Human
Immunogen: Cardiac Troponin I peptide (KISASRKLQLKT).
Specificity: This antibody binds specificially to the cardiac Troponin I Peptide KISASRKLQLKT. This epitope is 100% conserved among a great variety of mammalian species, including most monkeys, Squirrel, Hamster, Mouse, Rat, Rabbit, Whales, Mole-Rat, Antelope and several other mammals.
Application Notes: Troponin I is the inhibitory subunit of troponin, the thin filament complex that confers calcium-sensitivity to muscle-actomyoisin ATPase activity. Cardiac Troponin I in the blood is also a marker for several heart muscle damages including myocardial infarction.
Antibody First Published in:
Conroy et al. Journal of Biological Chemsitry 2014; 289(22):15384-15392 PMID:24737329 Note on publication: Describes the use of phage display libraries to generate chicken antibodies against human cardiac troponin and PSA with subsequent crystallisation.

Product Form

This is a Standard size product. Purified antibody.
Purification: Protein A affinity purified
Supplied in: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00434-1.1

Mouse IgG1

In stock
Standard size 200 µg
Custom conjugation:
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