Anti-Methylene diphenyl diisocyanate [DD10] Bulk size

Description: Recombinant monoclonal antibody to Methylene diphenyl diisocyanate. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma DD10.
Isotype and Format: Human IgG1, kappa
Clone Number: DD10
Published Application(s): ELISA; WB
Published Species Reactivity: Species independent
Immunogen: Mouse serum protein conjugated with MDI.
Specificity:
Application Notes: The antibody binds specifically to MDI, a low-molecular weight aromatic diisocyanate which is commonly used to make polyurethane. MDI is also a major cause of occupational asthma, due to its ability to sensitize the immune system and elicit an immune response. In humans, the carrier protein albumin is able to recognise and conjugate with MID, forming a complex which is bound by IgE, triggering an asthmatic attack. Monoclonal antibodies directed against MID can be applied to diagnostics and research,and can be used to detect and quantitate MID levels in blood and urine, as well as in environmental samples.
Antibody First Published in:
Wisnewski AV, Liu J. Mol Immunol. 2013 Jun;54(2):233-7. PMID:23295252 Note on publication: Describes the production of six monoclonal antibodies directed against MDI, which could be developed into useful diagnostic reagents.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00504-10.0-BT

Human IgG1

Ships in 4-6 weeks
Standard size 200 µg
Custom conjugation:
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