Anti-PCNA [PC10] Bulk size

Description: Recombinant monoclonal antibody to PCNA. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma PC10.
Isotype and Format: Mouse IgG2a, kappa
Clone Number: PC10
Published Application(s): FC; IHC; IF; IP; WB
Published Species Reactivity: Human; Insect; S. pombe
Immunogen: Protein A-PCNA fusion obtained from pC2T.
Specificity: This antibody binds to PCNA from various vertebrate, invertebrate and fungal species.
Application Notes: PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is potentially a therapeutic target in cancer therapy and a useful marker for identifying the proliferation status of tumour tissue (i.e. relevant to prognosis). This antibody can be used for grading of different neoplasms, e.g. astrocytoma. It can be of diagnostic and prognostic value. Recommended for use on formalin-fixed paraffin embedded sections. NEUTRAL ELUTE ONLY.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00605-2.0-BT

Mouse IgG2a

In stock
Standard size 200 µg
Custom conjugation:
Clear selection