Anti-GITR [YGITR765] Bulk size

Description: Recombinant monoclonal antibody to GITR. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YGITR765.
Isotype and Format: Mouse IgG2a, kappa
Clone Number: YGITR765
Published Application(s): FC; block
Published Species Reactivity: Mouse
Immunogen: nB2/6TG cells transfected with mouse GITR injected into DA rats.
Specificity: This antibody binds murine GITR.
Application Notes: A chimeric version of this antibody featuring a human IgG1 Fc-portion engineered to lack the N-linked glycosylation site at amino acid 297 was shown to have an agonistic effect on GITR signalling (Ponte 2010)
Antibody First Published in:
Cobbold et al. J Immunol. 2004 May 15;172(10):6003-10. PMID:15128783 Note on publication: Describes the use of this antibody in flow cytometry.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00631-2.0-BT

Mouse IgG2a

In stock
Standard size 200 µg
Custom conjugation:
Clear selection