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- Ab00643-2.0 Anti-Langerin [4C7]
- Pig, Human, Cynomolgus Monkey, Mouse
- Mouse IgG2a
- Purified
- In Stock
- Ab00643-23.0 Anti-Langerin [4C7]
- Pig, Human, Cynomolgus Monkey, Mouse
- Rabbit IgG
- Purified
- In Stock
Recombinant monoclonal antibody to Langerin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 4C7.
UniProt Accession Number of Target Protein: Q9UJ71
Alternative Name(s) of Target: CD207; C-type lectin domain family 4 member K; CLC4K
Immunogen: Langerin ectodomain fused to human IgFc
Specificity: This antibody binds to the ectodomain of Langerin (CD207).
Application Notes: This antibody can be used to identify Langerin-positive dendritic cells. This antibody has also been used to specifically target vaccine-peptides to dendritic cells.
Antibody first published in:
Flamar et al. Noncovalent assembly of anti-dendritic cell antibodies and antigens for evoking immune responses in vitro and in vivo. J Immunol. 2012 Sep 1;189(5):2645-55. PMID:22865916
Note on publication:
Describes the use of 4C7 in targeting vaccine antigens to dendritic cells.