United Kingdom (UK)
Recombinant monoclonal antibody to Der p 1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 10B9.
UniProt Accession Number of Target Protein: P08176
Alternative Name(s) of Target: Dust Mite Allergen; Der p 1: Dermatophagoides pteronissynus allergen 1; Allergen Der p 1; Allergen Der p I; Major mite fecal allergen Der p 1
Immunogen: Der p 1, a dust mite allergen.
Specificity: This antibody binds to a species-specific epitope in Der p 1, a dust mite allergen.
Application Notes: This antibody binds to a species-specific epitope on Der p 1. It may be used in conjunction with clone 5H8 in a sandwich assay. It also competes with clone 4C1 for binding to Der p 1, but with 4C1 binding to Der f 1. Fab versions of this antibody have been used in co-crystallization studies.
Antibody first published in:
Chapman et al. Epitope mapping of two major inhalant allergens, Der p I and Der f I, from mites of the genus Dermatophagoides. J Immunol. 1987 Sep 1;139(5):1479-84. PMID:2442247
Note on publication:
Describes comparative epitope mapping of various anti-Der p 1 and Der f 1 antibodies.