Anti-GM-CSF [GCC21] Standard size

Description: Recombinant monoclonal antibody to GM-CSF. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone GCC21. This antibody was created using our proprietary Fc Silent™ engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors.
Isotype and Format: Human IgG1, Fc Silent™, kappa
Clone Number: GCC21
Published Application(s): NTRL; Biacore; ELISA
Published Species Reactivity: Human
Immunogen: Antibody generated by sequencing of memory B-cells obtained from human patients suffering from chronic autoimmune pulmonary alveolar proteinosis.
Specificity: This antibody binds to human GM-CSF at a site distinct to clone GCA43.
Application Notes: This antibody binds to human GM-CSF and has neutralizing activity.
Antibody First Published in:
Piccoli et al. Nat Commun. 2015 Jun 16;6:7375 PMID:26077231 Note on publication: Describes the generation and characterization of this antibody.

Product Form

This is a Standard size product. Purified antibody.
Purification: Protein A affinity purified
Supplied in: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00685-10.3

Human IgG1

Ships in 2-3 weeks
Standard size 100 µg
Custom conjugation:
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