Anti-MERS-CoV Spike Protein [D12] Bulk size

Description: Recombinant monoclonal antibody to MERS-CoV Spike Protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma D12.
Isotype and Format: Rabbit IgG, kappa
Clone Number: D12
Published Application(s): NTRL; ELISA; Crystallization; IF
Published Species Reactivity: MERS-CoV
Immunogen: MERS-CoV (England1 strain) S1 protein.
Specificity: This antibody binds to MERS-CoV spike protein receptor binding domain on the S1 protein. It is reported to cross-reacts with MERS-CoV strains England1, Bishan1, England1-D509G, whilst binding to England1-S532P, W535R and E536R is impaired.
Application Notes: This antibody binds to MERS-spike protein receptor binding domain, and has neutralizing effect in an in vitro model and was elicited by a vaccine conferring long-lasting in vivo protection. This antibody does not work by Western Blot.
Antibody First Published in:
Wang et al. Nat Commun 6, 7712 (2015) PMID:26218507 Note on publication: Describes the generation as well as functional and structural characterization of this antibody.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab00696-23.0-BT

Rabbit IgG

Ships in 2-3 weeks
Standard size 200 µg
Custom conjugation:
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