Anti-Integrin alpha 4 [Natalizumab] Bulk size

Description: Recombinant monoclonal antibody to Integrin alpha 4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody Natalizumab.
Isotype and Format: Rabbit IgG, kappa
Clone Number: Natalizumab
Published Application(s): block; FC
Published Species Reactivity: Human
Immunogen: The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
Specificity: This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin

Antibody First Published in:
Sheremata et al. Neurology. 1999 Mar 23;52(5):1072-4. PMID:10102433 Note on publication: Describes the safety and pharmacokinetic characterization of this antibody in a clinical setting.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label