Anti-CTLA-4 [9D9] Bulk size

Description: Recombinant monoclonal antibody to CTLA-4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 9D9.
Isotype and Format: Rabbit IgG, kappa
Clone Number: 9D9
Published Application(s): block
Published Species Reactivity: Mouse
Immunogen: The antibody was raised against CTLA-4.
Specificity: The antibody is specific for CTLA-4.
Application Notes: The antbidoy has been used to block CTLA-4 and has been shown to enhance T-cell immunity against tumours (Quezada et al, 2006). 9D9 also has an anti-B16/BL6 melanoma effect in non-irradiated tumour-bearing recipients when given as combinatorial therapy with Gvax (Peggs et al, 2009).
Antibody First Published in:
Simpson T et al. J Exp Med. 2013 Aug 26; 210(9): 1695–1710. PMID:23897981 Note on publication: Describes the characterisation of the Fcγ receptor-dependent activity of 9D9 on the T reg cell compartment.

Product Form

This is a Bulk size product. Purified antibody in bulk size.
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4°C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20°C.
Concentration: See vial label

Product Code: Ab01018-23.0-BT

Rabbit IgG

Ships in 4-6 weeks
Standard size 200 µg
Custom conjugation:
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