Recombinant Versions of Naturally Occurring Formats

With our understanding of the structure-function-relationship of antibody domains we can combine naturally occurring antibody domains to generate reagents fulfilling specific requirements. Whether you would like to reduce immunogenicity of an antibody in in vivo applications by matching the constant region to the model organism used or would like to fine-tune antibody effector function by switching isotype, chimeric antibodies offer a range of possibilities now available for all our products.

Equally, we can expand the possible avenues of investigation in autoimmunity, allergy or primary immunodeficiencies by offering antibody formats beyond IgG, such as IgM, IgE, IgA and IgD.