A Question of Isotype: How Switching Antibody Isotypes and Fc Regions Promotes Discovery

How do you choose the right antibody format for your project beyond simply matching antibody and antigen? This white paper provides a discussion of how to select the right antibody format for your cancer research in live mouse models, with topics like: 

  • In vivo benefits of swapping antibody species 
  • Mouse IgG isotypes and subtypes 
  • Relative IgG subtype binding affinities to Fc receptors 
  • Fc region engineering for tailored effector function 
  • Optimal antibody formats for cancer targets like PD-1, CTLA-4, and more 


Download the white paper using the form below.   

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