Respiratory syncytial virus, more commonly referred to as RSV, is currently infecting an abnormally high number of people and pushing hospitals to capacity. This, coupled with COVID and the upcoming flu season, is leading public health officials to warn of a possible “tripledemic” come winter. Most RSV infections in adults cause a mild illness with cold-like symptoms, but in very young children it can cause pneumonia and bronchiolitis. Infants and older adults are the most at-risk of life-threatening complications (NPR, 2022).
But it’s not all bad news. According to a BioSpace article, Pfizer’s bivalent RSV vaccine has shown “…high efficacy against severe medically attended lower respiratory tract illness in infants…” and the company is planning to submit a Biologics License Application to the FDA by year end.
Engineered Recombinant Antibodies for RSV
Absolute Antibody is a leader in recombinant antibody technology and offers a variety of catalog RSV antibodies. In particular, our catalog includes research-grade biosimilars of the therapeutic antibodies Felvizumab and Palivizumab, as well as unique antibodies sequenced from RSV-infected patients, such as pre- and post-fusion conformations of the RSV F protein.
All the RSV antibodies are available recombinantly produced for ensured batch-to-batch reproducibility. Moreover, we have engineered the antibodies into new formats useful for research, with off-the-shelf offerings ranging from human, rabbit, mouse and ferret species to IgG, IgA and IgM isotypes, as well as fragments and Fc silenced antibodies.
This antibody engineering is enabled by our proprietary cloning system, which allows for rapid reformatting of antibodies into almost any format. If you do not see the antibody or format you need in our catalog, check out our custom antibody engineering services, which include chimerization, isotype switching, multispecifics, and engineered Fc domains.
RSV Reagents from Absolute Biotech
Absolute Antibody is now part of Absolute Biotech, a new company that unites multiple life science brands into one organization specializing in antibody reagents and services. Together, our family of brands is proud to offer a variety of antibodies, proteins, and reagents for RSV research. See what is offered below by LSBio and Kerafast, two of our sister companies.
The LSBio RSV catalog includes conjugated and unconjugated antibodies, as well as proteins and ELISA kits.
Kerafast makes unique laboratory-made research tools easily accessible to the global scientific community. Their catalog includes anti-RSV, nonstructural protein 1 (NS1) antibodies originally developed at the US National Institute of Allergy and Infectious Disease.
Contact us today for more information or to receive a quote.
Biologics UK – Booth #27
13-15th March 2024