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- Ab00407-1.1 Anti-AdiC [Fab21]
- E. coli, Salmonella enterica
- Mouse IgG1
- Purified
- Ships in 5-6 weeks
- Ab00407-1.4 Anti-AdiC [Fab21]
- E. coli, Salmonella enterica
- Mouse IgG1
- Fc Silent™
- Purified
- Ships in 5-6 weeks
Recombinant monoclonal antibody to AdiC. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma Fab21.
UniProt Accession Number of Target Protein: P60061
Alternative Name(s) of Target: Arginine:Agmantine Antiporter
Immunogen: E.coli AdiC.
Specificity: Binds to the AdiC transporter of various enteric bacteria, including E.coli and S. enterica.
Application Notes: This antibody binds to AdiC of enteric bacteria. AdiC is a membrane protein acting as a transporter that imports arginine from the gastric juice and exports its decarboxylation product agmatine along with protons. AdiC is responsible for the acid-resistance of enteric bacteria. The antibody does not inhibit function of the transporter.
Antibody first published in:
Fang et al. Structure of a prokaryotic virtual proton pump at 3.2 A resolution. Nature 2009; 460(7258):1040-1043 PMID:19578361
Note on publication:
Describes the crystallisation of AdiC, an L-arginine transporter, with the aid of an AdiC-binding Fab.