Anti-CD4 [13B8.2 (IOT4a)]

Description:

Recombinant monoclonal antibody to CD4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 13B8.2 (IOT4a).

Clone Name:

13B8.2 (IOT4a)

Published Application(s):

EIA, WB, ELISA, FC, IHC-Fr

Published Species Reactivity:

Human

Products based on this clone:

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Ab00241-1.1 Anti-CD4 [13B8.2 (IOT4a)]
Human
Mouse IgG1
Purified
In Stock

Ab00241-23.0 Anti-CD4 [13B8.2 (IOT4a)]
Human
Rabbit IgG
Purified
In Stock

UniProt Accession Number of Target Protein: P01730

Alternative Name(s) of Target: Leu3/T4
Immunogen: Human HSB2-T cells.

Specificity: Recognises human CD4.

Antibody first published in: Bes et al. Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1 FEBS Lett 2002 Feb 13;512(1-3):354. PMID:11707270
Note on publication: Describes the identification of sequence elements that mediate the immunosuppressive effect of this antibody.

Flow-cytometry on human lymphocytes using Ab00241. Click on image for more details.

Flow-cytometry using anti-CD4 antibody 13B8.2 (Ab00241) Human lymphocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of 13B8.2 (Ab00241-23.0, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.

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