United Kingdom (UK)
Recombinant monoclonal antibody to Collagen Type II. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma mAb 1-5.
UniProt Accession Number of Target Protein: Q91VF6
Alternative Name(s) of Target: COL2
Immunogen: Human recombinant collagen II.
Specificity: Binds specifically to human native type II collagen.
Application Notes: This antibody binds to human collagen type II, a fibrillar type of collagen and the main collagenous component of cartilage.
Antibody first published in:
Ito et al. Quaternary structure-dependent idiotope and antigen binding of a monoclonal antibody specific for conformational epitope on type II collagen. Cellular and Molecular Life Science 1997; 53(1)51-60 PMID:9117997
Note on publication:
Describes the generation of an anti-collagen II antibody that binds specifically to the native form.