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Recombinant monoclonal antibody to HSPB1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the B-cell cDNA library SAIC-23E-30.
UniProt Accession Number of Target Protein: P04792
Alternative Name(s) of Target: Heat shock protein beta-1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27, SRP27, HSP27, HSP28
Immunogen: Peptide "LFDQAFGLPR" derived from Heat shock protein beta-1, involved in stress resistance and actin organisation, conjugated to KLH.
Specificity: Recognises human HSPB1.
Application Notes: Original data characterizing this antibody may be found here .
Antibody first published in:
Schoenherr et al. Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA. Mol Cell Proteomics PMID:25512614
Note on publication:
Describes generation a panel of recombinant antibodies using synthetic peptides of human proteins as well as validation using ELISA and multiple reaction monitoring-mass spectrometry.