Anti-avian infectious bronchitis virus Nucleoprotein [C5P1]

Description:

Recombinant monoclonal antibody to avian infectious bronchitis virus Nucleoprotein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody C5P1.

Clone Name:

C5P1

Published Application(s):

WB, ELISA

Published Species Reactivity:

avian infectious bronchitis virus

Products based on this clone:

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Ab00970-1.1 Anti-avian infectious bronchitis virus Nucleoprotein [C5P1]
avian infectious bronchitis virus
Mouse IgG1
Purified
In Stock

Ab00970-23.0 Anti-avian infectious bronchitis virus Nucleoprotein [C5P1]
avian infectious bronchitis virus
Rabbit IgG
Purified
Ships in 4-5 weeks

UniProt Accession Number of Target Protein: Q98WJ7

Alternative Name(s) of Target: IBV; Q82616
Immunogen: This scFv was derived from a phage display library prepared against the IBV vaccine strain H120.

Specificity: This scFv recognises heterologous infectious bronchitis virus strains isolated from Brazilian (IBVPR01, IBVPR05) and American (SE-17) outbreaks.

Application Notes: The cross-reactivity of this scFV with a panel of heterologous infectious bronchitis virus strains has been confirmed in ELISA experiments (Fernandes et al, 2010). In Western blot analysis, this scFv has been shown to bind IBV nucleoprotein (Fernandes et al, 2010). This scFv could be employed in immunodiagnostic techniques.

Antibody first published in: Fernandes et al. Construction of an avian single chain monoclonal antibodies (scFv) library by phage display that cross-reacted with heterologous avian infectious bronchitis virus strains Cienc. Rural vol.40 no.6 Santa Maria June 2010 PMID:
Note on publication: Describes the original generation of this scFv by phage display, and characterisation of its specificity by ELISA and Western blotting.