United Kingdom (UK)
Recombinant monoclonal antibody to CA50. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma CA50Ab01.
Alternative Name(s) of Target: CA 50; Carbohydrate antigen 50; tumor marker
Immunogen: The original antibody was generated by immunizing mice with CA50 protein.
Specificity: This antibody binds tumor marker CA50. CA50 is a carbohydrate antigen that is mainly distributed in sugar esters and high molecular glycoprotein. CA50 is not organ-specific and elevated levels are seen in various conditions such as colitis, pancreatitis, pneumonia, and cancers, especially gastrointestinal cancers (e.g., pancreatic, stomach, hepatic, and colorectal cancers).
Application Notes: The binding reactivity of this antibody to CA50 tumor marker was determined using indirect ELISA. This antibody was also used in the immunofluorescence staining of pancreatic cancer cells expressing CA50 (CN108424455).
Antibody first published in: PMID: