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- Ab00246-10.0 Anti-DI/DII domain of Dengue E protein [DV18]
- Dengue Virus
- Human IgG1
- Purified
- Ships in 4-5 weeks
- Ab00246-23.0 Anti-DI/DII domain of Dengue E protein [DV18]
- Dengue Virus
- Rabbit IgG
- Purified
- In Stock
Recombinant monoclonal antibody to DI/DII domain of Dengue E protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone DV18.
Alternative Name(s) of Target: Envelope protein
Immunogen: Made by immortalizing IgG-expressing B cells Dengue Virus (DENV) patients after primary or secondary infection.
Specificity: This antibody specifically recognizes an epitope in the DI/DII domain of E protein of DENV-1, DENV-2, DENV-3 and DENV-4 serotypes. This antibody was isolated as a human IgG1 from a patient recovered from a secondary DENV-2 infection and neutralises infection.
Antibody first published in: Beltramello et al. The human immune response to Dengue Virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe. 2010 Sep 16;8(3):271-83. PMID:20833378