United Kingdom (UK)
Recombinant monoclonal antibody to E2 A domain. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the bone-marrow derived phage display antibody F5.
Alternative Name(s) of Target: VEEV envelope protein 2 domain A
Immunogen: This antibody that was isolated using phage display from human bone marrow donors.
Specificity: This antibody binds to the E2 A domain to an epitope mapped to amino acids 115 to 119.
Application Notes: This antibody has been shown to have protective effects in VEEV challenge and has been used in crystallization studies.
Antibody first published in:
Hunt et al. A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus J Gen Virol. 2006 Sep;87(Pt 9):2467-76. PMID:16894184
Note on publication:
Describes the generation of this antibody from a phage display library.