Anti-E2 A domain [F5]

Description:

Recombinant monoclonal antibody to E2 A domain. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the bone-marrow derived phage display antibody F5.

Clone Name:

Published Application(s):

crystallization, NTRL

Published Species Reactivity:

Human Venezuelan Equine Encephalitis Virus

Products based on this clone:

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Ab00707-10.0 Anti-E2 A domain [F5]
Human Venezuelan Equine Encephalitis Virus
Human IgG1
Purified
Ships in 4-5 weeks

Ab00707-23.0 Anti-E2 A domain [F5]
Human Venezuelan Equine Encephalitis Virus
Rabbit IgG
Purified
In Stock

Alternative Name(s) of Target: VEEV envelope protein 2 domain A
Immunogen: This antibody that was isolated using phage display from human bone marrow donors.

Specificity: This antibody binds to the E2 A domain to an epitope mapped to amino acids 115 to 119.

Application Notes: This antibody has been shown to have protective effects in VEEV challenge and has been used in crystallization studies.

Antibody first published in: Hunt et al. A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus J Gen Virol. 2006 Sep;87(Pt 9):2467-76. PMID:16894184
Note on publication: Describes the generation of this antibody from a phage display library.