United Kingdom (UK)
Recombinant monoclonal antibody to Ebola virus VP35 protein;. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 6c5.
UniProt Accession Number of Target Protein: Q05127
Alternative Name(s) of Target: EBOV VP 3
Immunogen: Ebola virus VP35.
Specificity: 6c5 is specific for the C-terminal portion of Zaire ebolavirus polymerase cofacter VP35 protein.
Application Notes: 6c5 was used in immunoblotting experiments to detect VP35 (Olsen et al, 2016). 6c5 has also been used in Western blot analysis to detect VP35 (Takamatsu et al, 2018; Cárdenas et al, 2006).
Antibody first published in:
Cárdenas et al, 2006. Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling J Virol. 2006 Jun;80(11):5168-78. PMID:16698997
Note on publication:
Describes the original generation of the antibody and its application to Western blotting.