Anti-FLNB [3F10]

Name: Anti-FLNB [3F10]
SKU: Ab04172
Availability: InStock

Description:

Recombinant monoclonal antibody to FLNB. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 3F10.

Clone Name:

3F10

Published Application(s):

BLI, ELISA

Published Species Reactivity:

Human

Products based on this clone:

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Ab04172-10.3 Anti-FLNB [3F10]
Human
Human IgG1
Fc Silent™
Purified
Ships in 5-6 weeks

Ab04172-10.0 Anti-FLNB [3F10]
Human
Human IgG1
Purified
Ships in 5-6 weeks

Ab04172-23.0 Anti-FLNB [3F10]
Human
Rabbit IgG
Purified
Ships in 5-6 weeks

Ab04172-2.0 Anti-FLNB [3F10]
Human
Mouse IgG2a
Purified
Ships in 5-6 weeks

Ab04172-2.3 Anti-FLNB [3F10]
Human
Mouse IgG2a
Fc Silent™
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: O75369

Alternative Name(s) of Target: Fh1; FLN-B; filamin B; Filamin-B; ABP-278; ABP-280 homolog; Actin-binding-like protein; Beta-filamin; Filamin homolog 1; Filamin-3; Thyroid autoantigen; Truncated actin-binding protein; Truncated ABP
Immunogen: The original antibody was generated by immunizing mice with FLNB antigen.

Specificity: The antibody is specific for FLNB. FLNB is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskeletal network, to control and guide proper skeletal development.

Application Notes: The specificity of the original format of the antibody was confirmed by ELISA analysis. The binding kinetics of the antibody to the full length FLNA protein was measured by BLI (Kd= 1 nM) (WO2018085441A1).

Antibody first published in: PMID: