Anti-Heart-type fatty acid-binding protein [HF2]

Description:

Recombinant monoclonal antibody to Heart-type fatty acid-binding protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma HF2.

Clone Name:

HF2

Published Application(s):

ELISA

Published Species Reactivity:

Human

UniProt Accession Number of Target Protein: P05413

Alternative Name(s) of Target: H-FABP; M-FABP; FABPH; FABP; FABP11; MDGI; Fatty acid-binding protein 3; Mammary-derived growth inhibitor; Fatty acid-binding protein; Muscle fatty acid-binding protein
Immunogen: The original antibody was generated by immunizing BLAB/c mice with human heart fatty acid binding protein isolated from human heart tissue.

Specificity: This antibody binds human heart fatty acid binding protein (H-FABP). Fatty acid binding protein (FABP) plays a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Application Notes: The reactivity of this antibody towards human H-FABP was tested using ELISA. This antibody can be used in combination with another antibody 11F10 for detection of H-FABP in a sample using sandwich ELISA. HF2 is used as coating antibody, and HF10 is labeled with HRP for detection. This antibody combination was also used for the preparation of a myocardial infarction kit for detection of H-FAPB in the sera of 26 patients (CN1978465).

Antibody first published in: PMID: