- Ab00271-10.0 Anti-HIV-1 GP41 [HGF24]
- Human IgG1
- Ships in 4-5 weeks
- Ab00271-23.0 Anti-HIV-1 GP41 [HGF24]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to HIV-1 GP41. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone HGF24.
Immunogen: Made by immortalizing IgG-expressing B cells from patients infected with diverse clades of HIV-1
Specificity: HIV-1 neutralising antibody, that binds to the HR-2 region within gp41 (glycoprotein 41). Binding has been mapped to the linear epitope "TNLIYTLIEESQN".
Antibody first published in: Corti et al. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals. PLoS One. 2010 Jan 20;5(1):e8805. doi: 10.1371/journal.pone.0008805. PMID:20098712