- Ab00725-3.0 Anti-IFN gamma [AF2]
- Mouse IgG2b
- In Stock
- Ab00725-10.0 Anti-IFN gamma [AF2]
- Human IgG1
- Enquire for Availability
- Ab00725-23.0 Anti-IFN gamma [AF2]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to IFN gamma. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma AF2.
UniProt Accession Number of Target Protein: P01579
Alternative Name(s) of Target: Interferon gamma; Immune interferon ; IFN-gamma; IFNG
Immunogen: Human IFNγ.
Specificity: The antibody binds to IFNγ with an IC50 of 65 pM and an affinity (Kd) of 19.3 nM.
Application Notes: The antibody binds specifically to IFNγ, a dimerised soluble cytokine member of the type II class of interferons synthesised by activated T-lymphocytes and natural killer (NK) cells. . IFNγ plays a role in both the innate and adaptive immune responses, an
Antibody first published in:
Thakur AB, Landolfi NF. A potent neutralizing monoclonal antibody can discriminate amongst IFNγ from various primates with greater specificity than can the human IFNγ receptor complex. Mol Immunol. 1999 Oct-Nov;36(15-16):1107-15. PMID:10698312
Note on publication: Describes the generation of the anti-IFNγ monoclonal antibody AF2, and its ability to neutralise the activity of IFNγ in humans compared to other primates.