Anti-Insulin-2 [193020]

Name: Anti-Insulin-2 [193020]
SKU: Ab03989
Availability: InStock

Description:

Recombinant monoclonal antibody to Insulin-2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 193020.

Clone Name:

193020

Published Application(s):

ELISA

Published Species Reactivity:

Mouse

Products based on this clone:

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Ab03989-23.0 Anti-Insulin-2 [193020]
Mouse
Rabbit IgG
Purified
Ships in 5-6 weeks

Ab03989-3.0 Anti-Insulin-2 [193020]
Mouse
Mouse IgG2b
Purified
Ships in 5-6 weeks

Ab03989-3.3 Anti-Insulin-2 [193020]
Mouse
Mouse IgG2b
Fc Silent™
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: P01326

Alternative Name(s) of Target: Insulin
Immunogen: The original antibody was generated by fusing spleen cells from two different NOD mice with recent onset diabetes with the mouse myeloma cell line NS-1.

Specificity: This antibody is specific for mouse insulin 2.

Application Notes: The activity of this anti-insulin autoantibody within supernatants was evaluated using ELISA (Pléau et al., 1993; PMID: 8413326).

Antibody first published in: Pléau et al. Evidence for antigen driven selection in two monoclonal auto-antibodies derived from nonobese diabetic mice Mol Immunol. 1993 Oct;30(14):1257-64. doi: 10.1016/0161-5890(93)90041-9 PMID:8413326
Note on publication: The original publication discusses the creation and characterization of two monoclonal autoantibodies directed against insulin and peripherin.