Anti-MUC1-C/ECD [8E1]

Description:

Recombinant monoclonal antibody to MUC1-C/ECD. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 8E1.

Clone Name:

8E1

Published Application(s):

WB, ELISA, FC

Published Species Reactivity:

Human

Products based on this clone:

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Ab03832-23.0 Anti-MUC1-C/ECD [8E1]
Human
Rabbit IgG
Purified
Ships in 5-6 weeks

Ab03832-10.0 Anti-MUC1-C/ECD [8E1]
Human
Human IgG1
Purified
Ships in 5-6 weeks

Ab03832-10.3 Anti-MUC1-C/ECD [8E1]
Human
Human IgG1
Fc Silent™
Purified
Ships in 5-6 weeks

Ab03832-1.1 Anti-MUC1-C/ECD [8E1]
Human
Mouse IgG1
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: P15941

Alternative Name(s) of Target: MUC1-C/extracellular domain; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3 (CA 15-3); Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6 (KL-6); PEMT; Peanut-reactive urinary mucin (PUM); Polymorphic epithelial mucin (PEM); Tumor-associated epithelial membrane antigen (EMA); Tumor-associated mucin
Immunogen: The original antibody was generated by immunizing C57Bl/6 mice with a protein containing ECD of MUC1-C fused to the Fc portion of mouse immunoglobulin (MUC1-C/ECD-mFc).

Specificity: The antibody is specific for MUC1-C/ECD.

Application Notes: The specificity of the original format of the antibody was confirmed by ELISA analysis. This antibody was used for detection of MUC1-C/ECD expressed on ZR-75-1 breast carcinoma cell lines by flow cytometry. The antibody detected the recombinant chIL-2 by western blot analysis (US10059775B2).

Antibody first published in: PMID: