Anti-Norovirus GII.4 VP1 [8E1]

Name: Anti-Norovirus GII.4 VP1 [8E1]
SKU: Ab02976
Availability: InStock

Description:

Recombinant monoclonal antibody to Norovirus GII.4 VP1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 8E1.

Clone Name:

8E1

Published Application(s):

neutralize, ELISA

Published Species Reactivity:

Norovirus

Products based on this clone:

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Ab02976-23.0 Anti-Norovirus GII.4 VP1 [8E1]
Norovirus
Rabbit IgG
Purified
In Stock

Ab02976-10.0 Anti-Norovirus GII.4 VP1 [8E1]
Norovirus
Human IgG1
Purified
Ships in 4-5 weeks

Ab02976-1.1 Anti-Norovirus GII.4 VP1 [8E1]
Norovirus
Mouse IgG1
Purified
Ships in 4-5 weeks

UniProt Accession Number of Target Protein: S5YAA0

Alternative Name(s) of Target: VP1; NoV; HuNoV; NoV VP1; capsid protein VP1; major capsid protein; Norovirus GII.4
Immunogen: The original antibody was generated by immunizing female BALB/c mice with virus like particles expressing Norovirus GII.4VP1 with an equal volume of aluminum adjuvant.

Specificity: This antibody reacts with the capsid protein VP1 of the Norovirus. Norovirus (NoVs) is one of the main pathogens causing sporadic cases and large outbreaks of acute gastroenteritis, and norovirus can infect people of all ages.

Application Notes: The binding characterization of this antibody for Norovirus GII.4 was done using ELISA. This antibody does not cross react with GI.1 virus-like particle in an ELISA. This antibody is capable of neutralizing Norovirus GII.4. This antibody is recommended for sensitive detection and analysis of Norovirus GII.4 (WO2016173558).

Antibody first published in: Zhong et al. Preparation and use of Anti-norovirus gii.4 type murine monoclonal antibody (WO2016173558). PMID:

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