- Ab01156-1.1 Anti-paclitaxel [1C2]
- Mouse IgG1
- In Stock
- Ab01156-23.0 Anti-paclitaxel [1C2]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to paclitaxel. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1C2.
Alternative Name(s) of Target: PT; PTX; Taxol; 7-Xylosylpaclitaxel; Taxol-7-xyloside; 7-xylosyltaxol
Immunogen: This antibody was raised by immunising BALB/c mice with a solution of 7-xylosyltaxol conjugated to the carrier protein bovine serum albumin (XylTax–BSA).7-xylosyltaxol is a taxol (paclitaxel) derivative, which binds to tubulin and inhibits microtubule dis
Specificity: This antibody is specific for paclitaxel, an anti-neoplastic agent derived from the Pacific yew.
Application Notes: The reactivity of this antibody for free and immobilised paclitaxel has been confirmed in ELISA analysis (Yusakul et al, 2018).
Antibody first published in:
Yusakul et al. Different expression systems resulted in varied binding properties of anti‑paclitaxel single‑chain variable fragment antibody clone 1C2 J Nat Med (2018) 72:310–316 PMID:29027080
Note on publication: Describes the original generation of this antibody, and the derivation of an scFv with the same binding specificity.