Anti-PDG7 [AIX-16]

Name: Anti-PDG7 [AIX-16]
SKU: Ab01226
Availability: InStock

Description:

Recombinant monoclonal antibody to PDG7. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody AIX-16.

Clone Name:

AIX-16

Published Application(s):

Published Species Reactivity:

Human

Products based on this clone:

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Ab01226-10.0 Anti-PDG7 [AIX-16]
Human
Human IgG1
Purified
Ships in 5-6 weeks

Ab01226-10.3 Anti-PDG7 [AIX-16]
Human
Human IgG1
Fc Silent™
Purified
Ships in 5-6 weeks

Ab01226-23.0 Anti-PDG7 [AIX-16]
Human
Rabbit IgG
Purified
Ships in 5-6 weeks

Immunogen: A phage library was constructed using peripheral blood lymphocytes from healthy human donors and tonsilar lymphocytes of children. Six rounds of affinity panning with PDG7 led to the selection of AIX-16.

Application Notes: Using flow cytometry it was showed that AI-X16 inhibits PDG7 binding to platelets (Escher et al, 1998).

Antibody first published in: Escher et al, 1998. Recombinant Anti-idiotypic Antibodies Inhibit Human Natural Anti-glycoprotein (GP)IIb/IIIa Autoantibodies J Autoimmun. 2002 Feb;18(1):71-81. PMID:11869049
Note on publication: Describes the production of the phage library and its application to flow cytometry.