United Kingdom (UK)
Recombinant monoclonal antibody to pre-fusion conformation of HRSV F protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone RSB20.
Alternative Name(s) of Target: RSV F; pre-fusion conformation of Respiratory syncytial virus F protein
Immunogen: Made by immortalizing IgG-expressing B cells from healthy patients.
Specificity: Antibody isolated as human IgG1. Neutralises HRSV-A2 with IC50 of 0.086 µg/ml.
Antibody first published in: Corti et al. Cross-neutralization of four paramyxoViruses by a human monoclonal antibody. Nature 501, 439–443 (2013). PMID:23955151